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Introduction Peripheral nerve injuries (PNIs), resulting from trauma or iatrogenic damage [1,2], can be severe and permanently debilitating, affecting over one million people every year worldwide [3]

doi: 10.3892/or.2019.7387 67 RigoulayC.EntenzaJ

Braune S, Krger-Genge A, Kammerer S, Jung F, Kpper JH

By binding to IGF-1R, IGF-1 can affect metabolism, cell growth (hypertrophy), differentiation and cell division (hyperplasia), prevention of cell death (apoptosis), normal development, and even malignant growth